The RadOnc Toolbox is a resource for health care professionals that is designed to support evidence-based practice. This point-of-care tool compiles frequently accessed references related to the delivery of radiation therapy, including dose constraints, calculators, toxicity scales, and clinical practice guidelines. The Radiation Oncology Toolbox is made possible through the generous and ongoing support by the Radiation Oncology Institute (ROI: www.roinstitute.org).