" Info e questionnairs include: · Record whether the patient brush his/her teeth · Self-monitoring the number of cigarettes smoked per day · Self-monitoring combustion free nicotine delivery system (C-F NDS) use · Self-monitoring the continuing of non-smoking · Monitoring the presence of Adverse Events (A/E) and Serious Adverse Events (SA/E) · Record whether the patient use dental floss · Record whether the patient use mouthwash · Record whether the patient changes something regarding your usually oral hygiene habit (i.e new toothbrush, new toothpaste, new mouthwash, etc..) Additionally, the SMILE app has several futures: · Practical Step-Counter, that will help you to monitoring your physical activity · Gamification system, with the possibility to win, collect and change virtual coins (Smile Coin) with amazing prizes · Reminder system, that serves to remember the date and the time of the next visit and all the restriction to follow · Possibility, whatever you want or need, to easily get in touch with your doctor The SMILE app is available just for Android users that are enrolled in “SMILE STUDY”, an 18-month duration clinical study supported by COEHAR. SMILE is FREE for the entire duration of the study."